Comparing an early cheap flight with a later airport that is easier to reach

The cheapest flight leaves at dawn from an airport that's awkward to reach. A later flight costs more but departs from a station-connected airport, so we could sleep normally and skip an expensive early taxi. Once I add baggage fees and transport, the price gap narrows. Do you compare these choices by total door-to-door cost and hours of sleep rather than ticket price? I'm leaning toward the less dramatic morning.